Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Randomized Controlled Trial
. 2017 Aug 2;17(1):286.
doi: 10.1186/s12888-017-1448-2.

Randomized controlled pilot trial of supportive text messages for patients with depression

Vincent I O Agyapong  1 , Michal Juhás  2 , Arto Ohinmaa  3 , Joy Omeje  4 , Kelly Mrklas  5 , Victoria Y M Suen  6 , Serdar M Dursun  2 , Andrew J Greenshaw  2
Affiliations
Randomized Controlled Trial

Randomized controlled pilot trial of supportive text messages for patients with depression

Vincent I O Agyapong et al. BMC Psychiatry. .

Abstract

Background: Depression is projected to be the primary cause of disability worldwide by 2030. In a recent survey, the most commonly cited unmet need among 42.4% of depressed Albertans was the lack of sufficient, accessible, and affordable counselling. Our aim was to test the efficacy of a supportive text messaging mobile health intervention in improving treatment outcomes in depressed patients.

Methods: We performed a single-rater-blinded randomized trial involving 73 patients with Major Depressive Disorder. Patients in the intervention group (n = 35) received twice-daily supportive text messages for 3 months while those in the control group (n = 38) received a single text message every fortnight thanking them for participating in the study. The primary outcome of this study was: "Mean changes in the BDI scores from baseline".

Results: After adjusting for baseline BDI scores, a significant difference remained in the 3 month mean BDI scores between the intervention and control groups: (20.8 (SD = 11.7) vs. 24.9 (SD = 11.5), F (1, 60) = 4.83, p = 0.03, ηp2 = 0.07). The mean difference in the BDI scores change was significant with an effect size (Cohen's d) of 0.67. Furthermore, after adjusting for baseline scores, a significant difference remained in the 3 month mean self-rated VAS scores (EQ-5D-5 L scale) between the intervention and control groups, 65.7 (SD = 15.3) vs. 57.4 (SD = 22.9), F (1, 60) =4.16, p = 0.05, ηp2 = 0.065. The mean difference in change mean self-rated VAS scores was also statistically significant with an effect size (Cohen's d) of 0.51.

Conclusions: Our findings suggest that supportive text messages are a potentially useful psychological intervention for depression, especially in underserved populations. Further studies are needed to explore the implications of our findings in larger clinical samples.

Trial registration: ClinicalTrials.gov NCT02327858 . Registered 24 December 2014.

Keywords: Depression; Mobile health; Randomised controlled trial; Supportive text messages; eHealth; mHealth.

PubMed Disclaimer

Conflict of interest statement

Authors’ information

Vincent I.O. Agyapong is a Clinical Associate Professor of Psychiatry at the Faculty of Health Sciences, Department of Psychiatry, University of Alberta and the Edmonton Zone Clinical Section Chief of Community Mental Health, Alberta Health Services, Edmonton, AB, Canada.

Michal Juhás is a PhD Candidate at the Faculty of Health Sciences, Department of Psychiatry, University of Alberta, Edmonton, AB, Canada.

Arto Ohinmaa is a Professor of Health Economics at Institute of Health Economics and School of Public Health, University of Alberta, Edmonton, AB, Canada.

Joy Omeje is staff member at the Department of Public Health, Alberta Health Services, Fort Mc Murray, AB, Canada.

Kelly Mrklas is a Knowledge Translation and Implementation Scientist at Research Priorities and Implementation, Research Innovation and Analytics, Alberta Health Services, Calgary, AB, Canada.

Victoria Y.M Suen is the Manager of the Addiction and Mental Health Strategic Clinical Network, Alberta Health Services, Edmonton, AB, Canada.

Serdar M. Dursun is a Professor of Psychiatry at the Faculty of Health Sciences, Department of Psychiatry, University of Alberta, Edmonton, AB, Canada.

Andrew J. Greenshaw is Professor of Psychiatry at the Faculty of Health Sciences, Department of Psychiatry, University of Alberta, Edmonton, AB, Canada.

Ethics approval and consent to participate

The study protocol was reviewed and approved by the Review and Ethics Board of the University of Alberta and written informed consent was obtained from all study participants.

Consent for publication

Not applicable.

Competing interests

All authors declare that they have no competing interests.

Publisher’s Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Figures

Fig. 1
Fig. 1
Study flow chart
See this image and copyright information in PMC

References

    1. Gap analysis of public mental health and addictions programs (GAP-MAP) final report http://www.deslibris.ca/ID/241268. Accessed 1 July 2016.
    1. Dewa CS, Goering P, Lin E, Paterson M. Depression-related short-term disability in an employed population. J Occup Environ Med. 2002;44(7):628–633. doi: 10.1097/00043764-200207000-00007. - DOI - PubMed
    1. Patten SB, Schopflocher D. Longitudinal epidemiology of major depression as assessed by the brief patient health questionnaire (PHQ-9) Compr Psychiatry. 2009;50(1):26–33. doi: 10.1016/j.comppsych.2008.05.012. - DOI - PubMed
    1. Slomp M, Jacobs P, Ohinmaa A, Bland R, Block R, Dewa CS, Wang C. The distribution of mental health service costs for depression in the Alberta population. Can J Psychiatr. 2012;57(9):564–569. doi: 10.1177/070674371205700907. - DOI - PubMed
    1. Caxaj CS. A review of mental health approaches for rural communities: complexities and opportunities in the Canadian context. Can J Commun Mental Health. 2016;35(1):29–45. doi: 10.7870/cjcmh-2015-023. - DOI

Publication types

Associated data