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Review
. 2017 Aug 3;21(1):198.
doi: 10.1186/s13054-017-1776-0.

Dexmedetomidine as a promising prevention strategy for cardiac surgery-associated acute kidney injury: a meta-analysis

Rui Shi  1 , Hong-Tao Tie  2
Affiliations
Review

Dexmedetomidine as a promising prevention strategy for cardiac surgery-associated acute kidney injury: a meta-analysis

Rui Shi et al. Crit Care. .
No abstract available

Keywords: Acute kidney injury; Cardiac surgery; Dexmedetomidine; Meta-analysis.

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Conflict of interest statement

Authors’ information

HTT is now working as a cardiothoracic surgeon in the Department of Cardiothoracic Surgery, The First Affiliated Hospital of Chongqing Medical University. HTT is also the young editor of the Chinese Journal of Clinical Thoracic and Cardiovascular Surgery and section editor of the Journal of Emergency and Critical Care Medicine. His major research interests include evidence-based medicine, critical care medicine, ischemia-reperfusion injury, and perioperative organ protection.

Ethics approval and consent to participate

Not applicable.

Consent for publication

Not applicable.

Competing interests

The authors declare that they have no competing interests.

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Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Figures

Fig. 1
Fig. 1
Forest plots for the meta-analysis of dexmedetomidine and the incidence of CSA-AKI
See this image and copyright information in PMC

Comment in

References

    1. Turan A, Bashour CA, You J, Kirkova Y, Kurz A, Sessler DI, et al. Dexmedetomidine sedation after cardiac surgery decreases atrial arrhythmias. J Clin Anesth. 2014;26(8):634–42. doi: 10.1016/j.jclinane.2014.05.009. - DOI - PubMed
    1. Balkanay OO, Goksedef D, Omeroglu SN, Ipek G. The dose-related effects of dexmedetomidine on renal functions and serum neutrophil gelatinase-associated lipocalin values after coronary artery bypass grafting: a randomized, triple-blind, placebo-controlled study. Interact Cardiovasc Thorac Surg. 2015;20(2):209–14. doi: 10.1093/icvts/ivu367. - DOI - PubMed
    1. Ji F, Li Z, Young JN, Yeranossian A, Liu H. Post-bypass dexmedetomidine use and postoperative acute kidney injury in patients undergoing cardiac surgery with cardiopulmonary bypass. PLoS One. 2013;8(10):e77446. doi: 10.1371/journal.pone.0077446. - DOI - PMC - PubMed
    1. Ammar AS, Mahmoud KM, Kasemy ZA, Helwa MA. Cardiac and renal protective effects of dexmedetomidine in cardiac surgeries: a randomized controlled trial. Saudi J Anaesth. 2016;10(4):395–401. doi: 10.4103/1658-354X.177340. - DOI - PMC - PubMed
    1. Cho JS, Shim JK, Soh S, Kim MK, Kwak YL. Perioperative dexmedetomidine reduces the incidence and severity of acute kidney injury following valvular heart surgery. Kidney Int. 2016;89:693–700. doi: 10.1038/ki.2015.306. - DOI - PubMed

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