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Case Reports
. 2017 Aug 2:2017:bcr2017221153.
doi: 10.1136/bcr-2017-221153.

Role of metastasectomy and chemotherapy in carcinoma of uterine cervix

Nasir Ali  1 , Muhammad Atif Mansha  1 , Ahmed Nadeem Abbasi  1 , Bilal Mazhar Qureshi  1
Affiliations
Case Reports

Role of metastasectomy and chemotherapy in carcinoma of uterine cervix

Nasir Ali et al. BMJ Case Rep. .

Abstract

Squamous cell carcinoma of uterine cervix is potentially a curable disease; however, many patients treated with definitive chemoradiotherapy develop distant metastases, with few of them having a single metastatic deposit. There are no guidelines for the treatment of patients with oligometastatic cervical cancer.We present a case of a patient with International Federation of Gynecology and Obstetrics (FIGO) Stage IIB squamous cell carcinoma of uterine cervix. She was successfully treated with concurrent chemoradiotherapy with definitive intent. One year later, she developed a solitary pulmonary nodule for which she underwent resection followed by chemotherapy. She is free of any local or distant disease at 5 years of regular follow-up.

Keywords: cervical cancer; gynecological cancer.

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Conflict of interest statement

Competing interests: None declared.

Figures

Figure 1
Figure 1
(A) H&E staining shows an infiltrating tumour arranged in nests with overlying endocervical columnar lining (B) Tumour cells are positive for p16 immunohistochemical stain.
Figure 2
Figure 2
Axial CT scan showing right lung base nodule.
Figure 3
Figure 3
(A) Metastatic squamous cell carcinoma to lung filling the alveoli. (B) Tumour cells showing nuclear positivity for p16 immunostain.
See this image and copyright information in PMC

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