Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2017 Aug 3;18(1):94.
doi: 10.1186/s12889-017-4644-6.

The incidence of acute myeloid leukemia in Calgary, Alberta, Canada: a retrospective cohort study

Andrea Christine Shysh  1 , Leonard Tu Nguyen  1 , Maggie Guo  2 , Marcus Vaska  3 , Christopher Naugler  1   2   4 , Fariborz Rashid-Kolvear  5   6   7
Affiliations

The incidence of acute myeloid leukemia in Calgary, Alberta, Canada: a retrospective cohort study

Andrea Christine Shysh et al. BMC Public Health. .

Erratum in

  • Erratum to: BMC Public Health, Vol. 18.
    [No authors listed] [No authors listed] BMC Public Health. 2017 Sep 22;17(1):736. doi: 10.1186/s12889-017-4709-6. BMC Public Health. 2017. PMID: 28938882 Free PMC article. No abstract available.

Abstract

Background: The incidence rate of acute myeloid leukemia (AML) was determined in the Calgary Metropolitan Area, a major Canadian city.

Methods: Data from all patients diagnosed with AML between January 1, 2011 and December 31, 2015 were retrieved from a single, centralized cancer cytogenetics laboratory for bone marrow samples, the sole diagnostic facility of its kind in Southern Alberta.

Results: The calculated incidence rate was 2.79 cases per 100,000 person-years with a median age of 60, slightly lower than previously published data. The age-standardized incidence rate for Canada was 3.46 cases per 100,000 person-years. The higher value is reflective of Calgary's younger population compared to the rest of Canada. Higher male incidence and greatest incidence occurring at approximately the age of 85 is similar to data from other developed countries. The lower incidence rates and median age of diagnosis, in comparison with that of other high-income nations, may be due to differences in the proportion of aging citizens in the population.

Conclusion: This is the first published incidence rate of acute myeloid leukemia (AML) in Canada across all age groups.

Keywords: Acute myelogenous leukemia; Acute myeloid leukemia; Canada; Cancer epidemiology; Hematological neoplasm, incidence.

PubMed Disclaimer

Conflict of interest statement

Ethics approval and consent to participate

Ethics approval for this study was obtained from the Health Research Ethics Board of the Alberta Cancer Committee (Ethics ID HREBA.CC-16-0830).

Consent for publication

Not applicable.

Competing interests

The authors declare that they have no competing interests.

Publisher’s Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Figures

Fig. 1
Fig. 1
Age and sex-categorized incidence rates of acute myeloid leukemia in the Calgary Metropolitan Area (2011–2015)
See this image and copyright information in PMC

References

    1. Globocan 2012: Estimated Cancer Incidence, Mortality and Prevalence Worldwide in 2012. Fact sheets by population. Lyon, France: World Health Organization International Agency for Research on Cancer. p. 2012.
    1. Alibhai SM, Leach M, Minden MD, Brandwein J. Outcomes and quality of care in acute myeloid leukemia over 40 years. Cancer. 2009;115(13):2903–2911. doi: 10.1002/cncr.24373. - DOI - PubMed
    1. Australian Cancer Incidence and Mortality (ACIM) books. Canberra, Australia: Australian Institute of Health and Welfare; 2016. http://www.aihw.gov.au/acim-books/.
    1. Acute myeloid leukaemia (AML) incidence statistics. London: Cancer Research UK; 2016. http://www.cancerresearchuk.org/health-professional/cancer-statistics/st....
    1. Australian Institute of Health and Welfare. Acute myeloid leukemia. Edmonton, AB: Alberta Health Services; 2016.