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. 2018 May;63(Suppl 1):109-121.
doi: 10.1007/s00038-017-1008-z. Epub 2017 Aug 3.

Burden of diarrhea in the Eastern Mediterranean Region, 1990-2015: Findings from the Global Burden of Disease 2015 study

GBD 2015 Eastern Mediterranean Region Diarrhea Collaborators
Collaborators

Burden of diarrhea in the Eastern Mediterranean Region, 1990-2015: Findings from the Global Burden of Disease 2015 study

GBD 2015 Eastern Mediterranean Region Diarrhea Collaborators. Int J Public Health. 2018 May.

Abstract

Objectives: Diarrheal diseases (DD) are an important cause of disease burden, especially in children in low-income settings. DD can also impact children's potential livelihood through growth faltering, cognitive impairment, and other sequelae.

Methods: As part of the Global Burden of Disease study, we estimated DD burden, and the burden attributable to specific risk factors and etiologies, in the Eastern Mediterranean Region (EMR) between 1990 and 2015. We calculated disability-adjusted life-years (DALYs)-the sum of years of life lost and years lived with disability-for both sexes and all ages.

Results: We estimate that over 103,692 diarrhea deaths occurred in the EMR in 2015 (95% uncertainty interval: 87,018-124,692), and the mortality rate was 16.0 deaths per 100,000 persons (95% UI: 13.4-19.2). The majority of these deaths occurred in children under 5 (63.3%) (65,670 deaths, 95% UI: 53,640-79,486). DALYs per 100,000 ranged from 304 (95% UI 228-400) in Kuwait to 38,900 (95% UI 25,900-54,300) in Somalia.

Conclusions: Our findings will guide evidence-based health policy decisions for interventions to achieve the ultimate goal of reducing the DD burden.

Keywords: Burden of disease; Diarrheal diseases; Eastern Mediterranean Region.

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Conflict of interest statement

This manuscript reflects original work that has not previously been published in whole or in part and is not under consideration elsewhere. All authors have read the manuscript and have agreed that the work is ready for submission and accept responsibility for its contents. The authors of this paper have complied with all ethical standards and do not have any conflicts of interest to disclose at the time of submission. The funding source played no role in the design of the study, the analysis and interpretation of data, and the writing of the paper. The study did not involve human participants and/or animals; therefore, no informed consent was needed.

The authors declare that they have no conflicts of interest at this time.

Figures

Fig. 1
Fig. 1
Diarrhea mortality rate per 100,000 population, by age, 1990–2015. The mortality rate in the Eastern Mediterranean Region is shown for six age groups over time from 1990 to 2015. Points represent mean estimates and error bars represent 95% uncertainty intervals (Global Burden of Disease 2015 study, Eastern Mediterranean Region, 1990–2015)
Fig. 2
Fig. 2
Diarrhea mortality among children under 5 in the Eastern Mediterranean Region, 2015. a The diarrhea mortality rate per 100,000 among children under 5 in 2015. b Ratio of the observed under 5 diarrhea mortality rate in 2015 to the expected mortality rate based on the Socio-demographic Index only. Values below 1 indicate that the diarrhea mortality rate is lower than would be expected based on the global relationship between mortality and SDI, and values above 1 indicate higher mortality rates than would be expected (Global Burden of Disease 2015 study, Eastern Mediterranean Countries, 2015)
Fig. 3
Fig. 3
The diarrhea mortality rate per 100,000 for the Eastern Mediterranean Region by country among children under 5 in 1990, 2000, and 2015. Countries are ordered from top to bottom from lowest Socio-demographic Index (Somalia) to highest SDI (Qatar) based on SDI values in 2015. Error bars illustrate the 95% uncertainty interval for the estimates (Global Burden of Disease 2015 study, Eastern Mediterranean Countries, 2015)
See this image and copyright information in PMC

References

    1. ACAPS (2015) Global emergency overview: November 2015. http://reliefweb.int/sites/reliefweb.int/files/resources/Global%20Emerge.... Accessed 12 Jul 2017
    1. Awqati NA, Ali MM, Al-Ward NJ, et al. Causes and differentials of childhood mortality in Iraq. BMC Pediatr. 2009;9:40. doi: 10.1186/1471-2431-9-40. - DOI - PMC - PubMed
    1. Enzley S, Barros F, UNICEF (1997) A global review of diarrhoeal disease control. https://www.unicef.org/evaldatabase/files/Global_1997_A_Global_Review.pdf. Accessed 12 Jul 2017
    1. Boschi-Pinto C, Velebit L, Shibuya K. Estimating child mortality due to diarrhoea in developing countries. Bull World Health Organ. 2008;86:710–717. doi: 10.1590/S0042-96862008000900015. - DOI - PMC - PubMed
    1. Charara R, Forouzanfar M, Naghavi M, et al. The burden of mental disorders in the Eastern Mediterranean Region, 1990–2013. PLoS One. 2017;12:e0169575. doi: 10.1371/journal.pone.0169575. - DOI - PMC - PubMed

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