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Multicenter Study
. 2017 Aug 20;130(16):1894-1901.
doi: 10.4103/0366-6999.211880.

Characteristics, Management, and Outcomes of Acute Heart Failure in the Emergency Department: A Multicenter Registry Study with 1-year Follow-up in a Chinese Cohort in Beijing

Guo-Gan Wang  1 , Si-Jia Wang  2 , Jian Qin  3 , Chun-Sheng Li  4 , Xue-Zhong Yu  5 , Hong Shen  6 , Li-Pei Yang  7 , Yan Fu  8 , Ya-An Zheng  9 , Bin Zhao  10 , Dong-Min Yu  11 , Fu-Jun Qin  12 , De-Gui Zhou  13 , Ying Li  14 , Fu-Jun Liu  15 , Wei Li  16 , Wei Zhao  17 , Xin Gao  1 , Zheng Wang  3 , Ming Jin  4 , Hong Zeng  4 , Yi Li  5 , Guo-Xing Wang  7 , Hong Zhou  8 , Xiao-Lu Sun  18 , Peng-Bo Wang  19 , Kam-Sang Woo  20
Affiliations
Multicenter Study

Characteristics, Management, and Outcomes of Acute Heart Failure in the Emergency Department: A Multicenter Registry Study with 1-year Follow-up in a Chinese Cohort in Beijing

Guo-Gan Wang et al. Chin Med J (Engl). .

Abstract

Background: The emergency department (ED) has a pivotal influence on the management of acute heart failure (AHF), but data concerning current ED management are scarce. This Beijing AHF Registry Study investigated the characteristics, ED management, and short- and long-term clinical outcomes of AHF.

Methods: This prospective, multicenter, observational study consecutively enrolled 3335 AHF patients who visited 14 EDs in Beijing from January 1, 2011, to September 23, 2012. Baseline data on characteristics and management were collected in the EDs. Follow-up data on death and readmissions were collected until November 31, 2013, with a response rate of 92.80%. The data were reported as median (interquartile range) for the continuous variables, or as number (percentage) for the categorical variables.

Results: The median age of the enrolled patients was 71 (58-79) years, and 46.84% were women. In patients with AHF, coronary heart disease (43.27%) was the most common etiology, and myocardium ischemia (30.22%) was the main precipitant. Most of the patients in the ED received intravenous treatments, including diuretics (79.28%) and vasodilators (74.90%). Fewer patients in the ED received neurohormonal antagonists, and 25.94%, 31.12%, and 33.73% of patients received angiotensin converting enzyme inhibitors/angiotensin receptor blockers, beta-blockers, and spironolactone, respectively. The proportions of patients who were admitted, discharged, left against medical advice, and died were 55.53%, 33.58%, 7.08%, and 3.81%, respectively. All-cause mortalities at 30 days and 1 year were 15.30% and 32.27%, respectively.

Conclusions: Substantial details on characteristics and ED management of AHF were investigated. The clinical outcomes of AHF patients were dismal. Thus, further investigations of ED-based therapeutic approaches for AHF are needed.

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Conflict of interest statement

There are no conflicts of interest.

Figures

Figure 1
Figure 1
The flowchart of the study. ED: Emergency department.
See this image and copyright information in PMC

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