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Comment
. 2017 Aug 3;21(2):159-160.
doi: 10.1016/j.stem.2017.07.002.

Cholangiocytes: No Longer Cinderellas to the Hepatic Regenerative Response

Malcolm R Alison  1
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Cholangiocytes: No Longer Cinderellas to the Hepatic Regenerative Response

Malcolm R Alison. Cell Stem Cell. .
Free article

Abstract

Biliary ductal cells proliferate from the portal areas of chronically damaged livers, but their significance to regeneration has been controversial. A recent article in Nature by Raven et al. (2017) now shows that blocking hepatocyte replication is essential for the hepatic differentiation of ductular cells after liver damage.

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