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. 2017 Dec;12(1):70.
doi: 10.1007/s11657-017-0364-x. Epub 2017 Aug 4.

Evaluation of bone mineral density in children with sickle-cell anemia and its associated factors in the south of Iran: a case-control study

Mohammad Reza Bordbar  1 , Sezaneh Haghpanah  1 , Tahereh Zarei  1 , Mohammad Hossein Dabbaghmanesh  2 , Gholamhossein Ranjbar Omrani  2 , Forough Saki  3
Affiliations

Evaluation of bone mineral density in children with sickle-cell anemia and its associated factors in the south of Iran: a case-control study

Mohammad Reza Bordbar et al. Arch Osteoporos. 2017 Dec.

Abstract

Sickle-cell anemia is a hereditary hemoglobin disorder among children. We showed that the low bone mass is prevalent among these children, and it has a negative association with hemoglobin. In spite of using supplementary 200 IU/day vitamin D, 59.6% of children with sickle-cell anemia are vitamin D deficient. We suggest that early diagnosis and treatment of this problem could improve the bone health in them.

Keywords: Children; Iran; Low bone mass; Sickle-cell anemia; Vitamin D.

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