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Case Reports
. 2017 Aug 7:2017:bcr2017221337.
doi: 10.1136/bcr-2017-221337.

An unusual cause of isolated secondary ovarian failure due to cerebral toxoplasmosis in an African woman with AIDS

Katie Tharshana Yoganathan  1 , Shaheena Sadiq  2 , Kathir G Yoganathan  3
Affiliations
Case Reports

An unusual cause of isolated secondary ovarian failure due to cerebral toxoplasmosis in an African woman with AIDS

Katie Tharshana Yoganathan et al. BMJ Case Rep. .

Abstract

Primary ovarian failure is common. However, isolated secondary ovarian failure due to gonadotrophin deficiency is rare. A few cases of isolated gonadotrophin deficiency, due to congenital cerebral toxoplasmosis, have been described in children. We report the case of a 34-year-old African woman positive for HIV, who developed secondary amenorrhoea following the successful treatment of cerebral toxoplasmosis. Investigations revealed that she developed an isolated gonadotrophin deficiency due to pituitary lesion. The rest of the pituitary function dynamic tests were normal.

Keywords: H\iv / Aids; infection (neurology); infections; pituitary disorders.

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Conflict of interest statement

Competing interests: None declared.

Figures

Figure 1
Figure 1
T1 postcontrast axial sequence shows a focal ring enhancing lesion in the right occipital lobe in keeping with an underlying abscess.
Figure 2
Figure 2
T1 sagittal postcontrast scan through pituitary stalk and gland was normal.
See this image and copyright information in PMC

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