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. 2017 Jul 19;5(4):427-431.
doi: 10.3889/oamjms.2017.114. eCollection 2017 Jul 25.

Madelung's Disease - Case Series and Treatment by Tumescent Liposuction or Lipectomy

Uwe Wollina  1 , Birgit Heinig  2
Affiliations

Madelung's Disease - Case Series and Treatment by Tumescent Liposuction or Lipectomy

Uwe Wollina et al. Open Access Maced J Med Sci. .

Abstract

Madelung disease is a disfiguring disorder belonging to the heterogeneous group of lipomatosis. The aetiology is not well understood, but alcohol consumption has been regarded as of importance. The reported incidence is about 1 in 25,000 inhabitants. We reviewed our files of the last ten years and identified eight adult patients with an equal gender distribution. Their age was between 60 and 85 years of life. Comorbidities are frequent. Clinical presentation may vary. Surgical treatment is reported and discussed. Both cold steel surgery and tumescent liposuction have their place in treatment.

Keywords: Lipomatosis; Madelung disease; adipose tissue; comorbidities; lipectomy; tumescent liposuction.

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Figures

Figure 1
Figure 1
Madelung’s disease with major disfigurement (Case 1). (a) Massive enlargement of subcutaneous adipose tissue under the chin; (b) Severe gynecomastia
Figure 2
Figure 2
Moderate growth of adipose tissue of the neck in Madelung’s disease with development of multiple telangiectasias (Case 2)
Figure 3
Figure 3
Improvement of Madelung’s disease by tumescent liposuction (Case 3). Before treatment (a, b) and after liposuction (c, d)
Figure 4
Figure 4
Moderate growth of subcutaneous adipose tissue with some telangiectasias (Case 4)
Figure 5
Figure 5
Massive tumor-like swelling of the neck (Case 5) with obvious telangiectasias (a). (b) Operation situs demonstrates non-encapsulated subcutaneous adipose tissue. (c) Resection specimen with massive enlarged adipocytes. (d) Two days after surgery
Figure 6
Figure 6
Pseudo-athletic appearance in Madelung’s disease (Case 6)
Figure 7
Figure 7
Fibrotic Madelung’s disease with dynamic growth (a and b), relapse after lipectomy; Stepwise improvement by tumescent liposuction from (c, d) to (e, f)
Figure 8
Figure 8
Massive disfigurement of the pseudo-athletic type of Madelung’s disease (Case 8)
See this image and copyright information in PMC

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