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. 2017 Aug 8;10(1):371.
doi: 10.1186/s13104-017-2682-x.

Clinical profile and comorbidity of traumatic brain injury among younger and older men and women: a brief research notes

Vincy Chan  1   2 , Tatyana Mollayeva  3   4 , Kenneth J Ottenbacher  5 , Angela Colantonio  1   2
Affiliations

Clinical profile and comorbidity of traumatic brain injury among younger and older men and women: a brief research notes

Vincy Chan et al. BMC Res Notes. .

Abstract

Objective: Comorbid disorders influence the course and outcomes of rehabilitation following traumatic brain injury (TBI), yet sex- and age-related disparities in the frequency distribution of these disorders remain poorly understood. We aimed to describe comorbid disorders by the International Classification of Diseases in patients with TBI undergoing inpatient rehabilitation in Ontario, Canada over a 3-year period, by sex and age, and discuss their potential impact on rehabilitation outcomes.

Results: The percentage of TBI patients with one or more comorbid disorder is higher among older (≥65 years) men and women than among those who are younger or middle-aged (<65 years). Among younger and middle-aged patients, multiple injuries and trauma, mental health conditions, and nervous system disorders were the most prevalent comorbidities. In older patients, circulatory, endocrine, nutritional, metabolic, and immune disorders were the most prevalent comorbidities. Our results suggest that a multisystem view of rehabilitation of men and women with TBI across age categories is needed to reflect the complex clinical profile of TBI patients undergoing rehabilitation.

Keywords: Age; Comorbidity; Index disease; Inpatient rehabilitation; Multimorbidity; Prevalence; Sex; Traumatic brain injury.

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Figures

Fig. 1
Fig. 1
ICD-10 categories of comorbid conditions in younger and older males and females with TBI. Categories of comorbid conditions in younger [<65 years of age (yoa)] and older (≥65 yoa) males and females with TBI in inpatient rehabilitation in Ontario, Canada 2004/05–2007/08. For each patient, multiple comorbidities were included. Regardless of age, sex differences at the p < 0.001 after Bonferroni correction were observed in disorders of the Endocrine, Nutritional, Metabolic and Immune System, Circulatory System, Musculo-skeletal system, and the Symptoms, Signs, and Ill-defined conditions. In the younger age group, sex differences at the p < 0.001 after Bonferroni correction were observed in Symptoms, Signs, and Ill-defined conditions, and in the older age group, in disorders of the Musculo-skeletal system
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References

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