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Multicenter Study
. 2018 Mar;71(3):170-177.
doi: 10.1016/j.rec.2017.04.035. Epub 2017 Aug 5.

Association of General and Abdominal Obesity With Hypertension, Dyslipidemia and Prediabetes in the PREDAPS Study

[Article in English, Spanish]
F Javier Sangrós  1 Jesús Torrecilla  2 Carolina Giráldez-García  3 Lourdes Carrillo  4 José Mancera  5 Teresa Mur  6 Josep Franch  7 Javier Díez  8 Albert Goday  9 Rosario Serrano  10 F Javier García-Soidán  11 Gabriel Cuatrecasas  12 Dimas Igual  13 Ana Moreno  14 J Manuel Millaruelo  1 Francisco Carramiñana  14 Manuel Antonio Ruiz  15 Francisco Carlos Pérez  10 Yon Iriarte  16 Ángela Lorenzo  17 María González  18 Beatriz Álvarez  19 Lourdes Barutell  19 M Soledad Mayayo  10 Mercedes Del Castillo  19 Emma Navarro  20 Fernando Malo  21 Ainhoa Cambra  22 Riánsares López  23 M Ángel Gutiérrez  24 Luisa Gutiérrez  25 Carmen Boente  11 J Javier Mediavilla  26 Luis Prieto  27 Luis Mendo  28 M José Mansilla  10 Francisco Javier Ortega  29 Antonia Borras  30 L Gabriel Sánchez  31 J Carlos Obaya  32 Margarita Alonso  33 Francisco García  34 Ángela Trinidad Gutiérrez  35 Ana M Hernández  35 Dulce Suárez  35 J Carlos Álvarez  36 Isabel Sáenz  37 F Javier Martínez  38 Ana Casorrán  39 Jazmín Ripoll  39 Alejandro Salanova  39 M Teresa Marín  40 Félix Gutiérrez  2 Jaime Innerárity  41 M Del Mar Álvarez  41 Sara Artola  41 M Jesús Bedoya  41 Santiago Poveda  42 Fernando Álvarez  43 M Jesús Brito  44 Rosario Iglesias  45 Francisca Paniagua  5 Pedro Nogales  46 Ángel Gómez  47 José Félix Rubio  47 M Carmen Durán  48 Julio Sagredo  49 M Teresa Gijón  50 M Ángeles Rollán  50 Pedro P Pérez  51 Javier Gamarra  52 Francisco Carbonell  53 Luis García-Giralda  54 J Joaquín Antón  54 Manuel de la Flor  55 Rosario Martínez  56 José Luis Pardo  57 Antonio Ruiz  58 Raquel Plana  59 Ramón Macía  60 Mercè Villaró  6 Carmen Babace  61 José Luis Torres  61 Concepción Blanco  62 Ángeles Jurado  63 José Luis Martín  63 Jorge Navarro  64 Gloria Sanz  65 Rafael Colas  66 Blanca Cordero  67 Cristina de Castro  67 Mercedes Ibáñez  68 Alicia Monzón  69 Nuria Porta  6 María Del Carmen Gómez  70 Rafael Llanes  71 J José Rodríguez  72 Esteban Granero  73 Manuel Sánchez  73 Juan Martínez  74 Patxi Ezkurra  75 Luis Ávila  76 Carlos de la Sen  77 Antonio Rodríguez  78 Pilar Buil  79 Paula Gabriel  80 Pilar Roura  80 Eduard Tarragó  81 Xavier Mundet  82 Remei Bosch  83 J Carles González  84 M Isabel Bobé  85 Manel Mata  85 Irene Ruiz  86 Flora López  87 Marti Birules  88 Oriol Armengol  88 Rosa Mar de Miguel  89 Laura Romera  90 Belén Benito  7 Neus Piulats  7 Beatriz Bilbeny  7 J José Cabré  91 Xavier Cos  92 Ramón Pujol  93 Mateu Seguí  94 Carmen Losada  95 A María de Santiago  96 Pedro Muñoz  97 Enrique Regidor  98
Affiliations
Multicenter Study

Association of General and Abdominal Obesity With Hypertension, Dyslipidemia and Prediabetes in the PREDAPS Study

[Article in English, Spanish]
F Javier Sangrós et al. Rev Esp Cardiol (Engl Ed). 2018 Mar.

Abstract

Introduction and objectives: Some anthropometric measurements show a greater capacity than others to identify the presence of cardiovascular risk factors. This study estimated the magnitude of the association of different anthropometric indicators of obesity with hypertension, dyslipidemia, and prediabetes (altered fasting plasma glucose and/or glycosylated hemoglobin).

Methods: Cross-sectional analysis of information collected from 2022 participants in the PREDAPS study (baseline phase). General obesity was defined as body mass index ≥ 30kg/m2 and abdominal obesity was defined with 2 criteria: a) waist circumference (WC) ≥ 102cm in men/WC ≥ 88cm in women, and b) waist-height ratio (WHtR) ≥ 0.55. The magnitude of the association was estimated by logistic regression.

Results: Hypertension showed the strongest association with general obesity in women (OR, 3.01; 95%CI, 2.24-4.04) and with abdominal obesity based on the WHtR criterion in men (OR, 3.65; 95%CI, 2.66-5.01). Hypertriglyceridemia and low levels of high-density lipoprotein cholesterol showed the strongest association with abdominal obesity based on the WHtR criterion in women (OR, 2.49; 95%CI, 1.68-3.67 and OR, 2.70; 95%CI, 1.89-3.86) and with general obesity in men (OR, 2.06; 95%CI, 1.56-2.73 and OR, 1.68; 95%CI, 1.21-2.33). Prediabetes showed the strongest association with abdominal obesity based on the WHtR criterion in women (OR, 2.48; 95%CI, 1.85-3.33) and with abdominal obesity based on the WC criterion in men (OR, 2.33; 95%CI, 1.75-3.08).

Conclusions: Abdominal obesity indicators showed the strongest association with the presence of prediabetes. The association of anthropometric indicators with hypertension and dyslipidemia showed heterogeneous results.

Keywords: Abdominal obesity; Anthropometric measurements; Disorder of lipid metabolism; Estado prediabético; Hipertensión; Hypertension; Medidas antropométricas; Obesidad; Obesidad abdominal; Obesity; Prediabetes; Trastorno del metabolismo de los lípidos.

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