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Case Reports
. 2017 Oct;23(10):1731-1732.
doi: 10.3201/eid2310.161398. Epub 2017 Oct 17.

Bedaquiline and Linezolid for Extensively Drug-Resistant Tuberculosis in Pregnant Woman

Marie Jaspard, Elisabeth Elefant-Amoura, Isabelle Melonio, Inés De Montgolfier, Nicolas Veziris, Eric Caumes
Case Reports

Bedaquiline and Linezolid for Extensively Drug-Resistant Tuberculosis in Pregnant Woman

Marie Jaspard et al. Emerg Infect Dis. 2017 Oct.

Abstract

A woman with extremely drug-resistant tuberculosis treated with a drug regimen including linezolid and bedaquiline during her last 3 weeks of pregnancy gave birth to a child without abnormalities. No fetal toxicities were noted by 2 years after delivery. This drug combination might be safe during the late third trimester of pregnancy.

Keywords: France; Georgia; MDR TB; Mycobacterium tuberculosis; XDR TB; antimicrobial resistance; bacteria; bedaquiline; case study; linezolid; multidrug-resistant tuberculosis; mycobacteria; pregnancy; respiratory infections; tuberculosis.

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