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Review
. 2017 Aug 9;9(8):847.
doi: 10.3390/nu9080847.

Personalised Interventions-A Precision Approach for the Next Generation of Dietary Intervention Studies

Affiliations
Review

Personalised Interventions-A Precision Approach for the Next Generation of Dietary Intervention Studies

Baukje de Roos et al. Nutrients. .

Abstract

Diet is a key modifiable risk factor for non-communicable diseases. However, we currently are not benefitting from the full potential of its protective effects. This is due to a number of reasons, including high individual variability in response to certain diets. It is now well acknowledged that in order to gain the full benefit of dietary regimes it is essential to take into account individual responses. With this in mind, the present review examines the concept of precision nutrition and the performance of n-of-1 studies, and discusses the development of certain approaches that will be critical for development of the concepts.

Keywords: bioavailability; dietary advice; dietary efficacy; metabolomics; nutrigenetics; personalised nutrition; phenotyping; precision nutrition.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Concept of n-of-1 trials leading to personalised interventions.

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