Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2017 Aug 9;9(8):850.
doi: 10.3390/nu9080850.

The Role of Nutritional Aspects in Food Allergy: Prevention and Management

Affiliations
Review

The Role of Nutritional Aspects in Food Allergy: Prevention and Management

Alessandra Mazzocchi et al. Nutrients. .

Abstract

The prevalence of food allergy in childhood appears to be increasing in both developed and transitional countries. The aim of this paper is to review and summarise key findings in the prevention and management of food allergy, focusing on the role of dietary components and nutritional habits in the development and optimal functioning of the immune system. Essential fatty acids, zinc and vitamin D are likely to enhance the anti-inflammatory and antioxidative barrier and promote immunologic tolerance. Additionally, nutritional components such as pre- and probiotics represent a novel research approach in the attempt to induce a tolerogenic immune environment. For all these reasons, the traditional avoidance diet has been, in recent years, completely reconsidered. New findings on the protective effect of an increased diversity of food introduced in the first year of life on allergic diseases are consistent with the hypothesis that exposure to a variety of food antigens during early life might play a role in the development of immune tolerance. Accordingly, therapeutic (and even preventive) interventions should be planned on an individual basis.

Keywords: adequate nutrition; children; diet diversity; food allergy.

PubMed Disclaimer

Conflict of interest statement

The authors declare no conflict of interest.

References

    1. Medicine Io. Food Allergies: Global Burden, Causes, Treatment, Prevention and Public Policy Washington: National Academy of Sciences. [(accessed on 28 March 2017)];2016 Available online: http://www.nationalacademies.org/hmd/Activities/Nutrition/FoodAllergies.....
    1. Venter C., Pereira B., Voigt K., Grundy J., Clayton C.B., Higgins B., Arshad S.H., Dean T. Prevalence and cumulative incidence of food hypersensitivity in the first 3 years of life. Allergy. 2008;63:354–359. doi: 10.1111/j.1398-9995.2007.01570.x. - DOI - PubMed
    1. Venter C., Patil V., Grundy J., Glasbey G., Twiselton R., Arshad S.H., Dean T. Prevalence and cumulative incidence of food hypersensitivity in the first ten years of life. Pediatr. Allergy Immunol. 2016;27:452–458. doi: 10.1111/pai.12564. - DOI - PubMed
    1. Nwaru B.I., Hickstein L., Panesar S.S., Muraro A., Werfel T., Cardona V., Dubois A.E., Halken S., Hoffmann-Sommergruber K., Poulsen L.K., et al. The epidemiology of food allergy in Europe: A systematic review and meta-analysis. Allergy. 2014;69:62–75. doi: 10.1111/all.12305. - DOI - PubMed
    1. Venter C., Pereira B., Grundy J., Clayton C.B., Roberts G., Higgins B., Dean T. Incidence of parentally reported and clinically diagnosed food hypersensitivity in the first year of life. J. Allergy Clin. Immunol. 2006;117:1118–1124. doi: 10.1016/j.jaci.2005.12.1352. - DOI - PubMed