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Comment
. 2017 Aug 9;26(145):170033.
doi: 10.1183/16000617.0033-2017. Print 2017 Sep 30.

Supplemental oxygen and dypsnoea in interstitial lung disease: absence of evidence is not evidence of absence

Michele R Schaeffer  1   2 , Yannick Molgat-Seon  1   3 , Christopher J Ryerson  1   4 , Jordan A Guenette  5   2   3
Affiliations
Comment

Supplemental oxygen and dypsnoea in interstitial lung disease: absence of evidence is not evidence of absence

Michele R Schaeffer et al. Eur Respir Rev. .

Abstract

Previous methodological flaws led to erroneous conclusions on the effects of oxygen on exertional dyspnoea in ILD http://ow.ly/Y48d30dCMk9

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Conflict of interest statement

Conflict of interest: Disclosures can be found alongside this article at err.ersjournals.com

Figures

FIGURE 1
FIGURE 1
a) Dyspnoea response at rest, iso-time, and peak exercise in 20 patients with fibrotic interstitial lung disease during constant work-rate cycle exercise testing while breathing 60% oxygen or room air. There was a statistically significant improvement in dyspnoea at iso-time but no change at peak exercise. Data are presented as mean±sem. *: p<0.05. b) Dyspnoea ratings every 2 min during constant load cycling in an individual patient while breathing 60% oxygen or room air. Dyspnoea ratings were reduced at all submaximal exercise times but the rating was increased at peak exercise. The Borg dyspnoea scale ranges from 0 to 10. Data from [13].
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References

    1. Bell EC, Cox NS, Goh N, et al. Oxygen therapy for interstitial lung disease: a systematic review. Eur Respir Rev 2017; 26: 160080. - PMC - PubMed
    1. Cao M, Wamboldt FS, Brown KK, et al. Supplemental oxygen users with pulmonary fibrosis perceive greater dyspnea than oxygen non-users. Multidiscip Respir Med 2015; 10: 37. - PMC - PubMed
    1. Nishiyama O, Miyajima H, Fukai Y, et al. Effect of ambulatory oxygen on exertional dyspnea in IPF patients without resting hypoxemia. Respir Med 2013; 107: 1241–1246. - PubMed
    1. Frank RC, Hicks S, Duck AM, et al. Ambulatory oxygen in idiopathic pulmonary fibrosis: of what benefit? Eur Respir J 2012; 40: 269–270. - PubMed
    1. Visca D, Montgomery A, de Lauretis A, et al. Ambulatory oxygen in interstitial lung disease. Eur Respir J 2011; 38: 987–990. - PubMed

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