Further linkage data on cystic fibrosis: the Utah Study
- PMID: 2879438
- PMCID: PMC1684126
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Further linkage data on cystic fibrosis: the Utah Study
Am J Hum Genet.
1986 Dec.
Abstract
We reported earlier complete linkage between cystic fibrosis and an RFLP of the met proto-oncogene revealed by the probe pmetH. Another clone, pmetD, detects another polymorphism with the TaqI restriction enzyme. Further linkage studies, now involving 22 families, have confirmed the tight linkage of cystic fibrosis to the MET and D7S8 loci. Significant allelic association was found between CF and allelic series defined by the pmetH probe.
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