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Review
. 2017 Jul 28:6:1272.
doi: 10.12688/f1000research.11337.1. eCollection 2017.

Hidradenitis suppurativa: an update on connecting the tracts

Mallory K Smith  1 , Cynthia L Nicholson  2 , Angela Parks-Miller  2 , Iltefat H Hamzavi  2
Affiliations
Review

Hidradenitis suppurativa: an update on connecting the tracts

Mallory K Smith et al. F1000Res. .

Abstract

Hidradenitis suppurativa (HS) is a devastating disease involving abscesses, sinus tracts, and inflammation classically affecting the axilla, groin, and/or anogenital region. Although the disease pathogenesis is not fully understood, recent advances suggest that HS pathology runs much deeper than the cutaneous manifestations. It is now believed that HS is a systemic inflammatory disease that gives rise to the characteristic cutaneous manifestations. This disease is problematic for both patients and physicians to manage because of a variety of diagnostic and management difficulties. This article seeks to provide updates on the current understanding of HS to increase awareness and improve management.

Keywords: comorbidities; hidradenitis suppurativa; mental health; pathophysiology; sexual health; treatment; update.

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Conflict of interest statement

Competing interests: Iltefat Hamzavi is the current president of the Hidradenitis Suppurativa Foundation (non-funded) and was an investigator for AbbVie. Angela Miller has served on an advisory board and as a consultant for AbbVie and is an employee of the Hidradenitis Suppurativa Foundation. Cynthia Nicholson and Mallory Smith declare that they do not have any competing interests.No competing interests were disclosed.Competing interests: Christopher Sayed has held roles with Abbvie Inc. as a speaker, Advisory Board Member and co-investigator.No competing interests were disclosed.

Figures

Figure 1.
Figure 1.. Henry Ford Hospital hidradenitis suppurativa (HS) treatment algorithm.
This treatment algorithm is used in the Henry Ford Dermatology Clinic, which provides care to more than 1,000 patients with HS. The algorithm is based on a combination of evidence-based research and provider experience. BID, bis in die; I/L, intralesional; IV, intravenously; Nd:YAG, neodymium-doped yttrium aluminum garnet; QD, quaque die.
See this image and copyright information in PMC

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    2. F1000 Recommendation

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