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. 2017 Jul;5(3):160-164.

Inferior Vena Cava Reconstruction by Gallbladder Patch: An Experimental Design

Hossein Hodjati  1 , Sahar Sohrabi Nazari  2 , Seifollah Dehghani Nazhvani  3 , Mohammad Yasin Karami  4 , Bita Geramizadeh  5
Affiliations

Inferior Vena Cava Reconstruction by Gallbladder Patch: An Experimental Design

Hossein Hodjati et al. Bull Emerg Trauma. 2017 Jul.

Abstract

Objective: To evaluate the efficacy of the gallbladder for reconstruction of the inferior vena cava in a canine model.

Methods: The experimental study was conducted on 5 dogs; an oval window with a diameter of (4×1 cm) was made in the inferior vena cava and then repaired using the autologous gallbladder patch with preservation of gallbladder function. The patency and functionality of the graft were assessed macroscopically and microscopically at 2 months postoperatively.

Results: All the dogs were euthanized at 2 months, showing excellent patency of the vena cava macroscopically. In the microscopic examination, all the patches were completely endothelialized. No evidence of infection and inflammation and thrombosis was noted.

Conclusion: The gallbladder patch is an available and safe alternate for reconstruction of the inferior vena cava at least in animal model. However, further well designed prospective studies are needed to confirm this hypothesis.

Keywords: Experimental design; Gallbladder; Inferior vena cava; Patch.

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Conflict of interest statement

The authors had no conflict of interest.

Figures

Fig.1
Fig.1
Inferior Vena Cava Reconstruction by Gallbladder serosal patch. IVC: Inferior Vena Cava, GB: Gallbladder, arrow: Suture line
Fig. 2
Fig. 2
A. Reconstructed inferior vena cava (arrow) with autologous gallbladder patch; B. The patent lumen of inferior vena cava (left arrow), gallbladder (right arrow)
Fig. 3
Fig. 3
A. Sections from the gall bladder patch can be seen in the left, arrow show the endothelialized part (*). There is no inflammation of fibrosis. B. Sections in the right side show the native vein, the arrow shows the native endothelium. (H&EX 100
See this image and copyright information in PMC

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