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. 2016 Mar 17:7:794-797.
doi: 10.1016/j.dib.2016.03.047. eCollection 2016 Jun.

Data showing phenotypic profile of uropathogenic Escherichia coli isolates from sepsis patients

Vivek Verma  1 , D Nagarjuna  1 , Gajanand Mittal  2 , Parveen Kumar  1 , Rakesh Singh Dhanda  3 , Rajni Gaind  2 , Manisha Yadav  1
Affiliations

Data showing phenotypic profile of uropathogenic Escherichia coli isolates from sepsis patients

Vivek Verma et al. Data Brief. .

Abstract

Bacterial virulence factors (VFs) influence the site and severity of urinary tract infections (UTI) and further leading to sepsis infection. Phenotypic characterisation of VFs specific to sepsis Escherichia coli strains has not been characterized in Indian population till date. In this data article, we have described important VFs of uropathogenic E. coli (UPEC) that is P fim, Type-1 fim, cell surface hydrophobicity, mannose resistant haemagglutination/mannose sensitive haemagglutination (MRHA/MSHA) expression and α-haemolysin production. The data includes a profile of the five VFs investigated in E. coli isolates from sepsis patients (N=78) and control group (N=50) from non-sepsis subjects. We found that P fim phenotype was expressed in 25.3% of E. coli isolates from sepsis patients, whereas Type-1 fimbriae was detected in 30.5%. Cell surface hydrophobicity phenotype was present in 30.5%, α-haemolysin in 26.3% and MRHA/MSHA in 22.1% of sepsis E. coli isolates. None of the control E. coli isolates showed presence of these phenotypes. The combined phenotypic profile of all the five VFs was significantly higher in sepsis patients as compared to the control group.

Keywords: Escherichia coli; Phenotypes; Sepsis.

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Figures

Fig. 1.
Fig. 1
(A) The phenotype profile of five important virulence factors of E. coli in sepsis patients and control group. (B) Combined virulence profile of sepsis E. coli samples as compared to control group.
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