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. 1987 Jan 24;1(8526):193-4.
doi: 10.1016/s0140-6736(87)90005-5.

Dengue virus isolation by antibody-dependent enhancement of infectivity in macrophages

M J Cardosa

Dengue virus isolation by antibody-dependent enhancement of infectivity in macrophages

M J Cardosa. Lancet. .

Abstract

Acute-phase serum samples collected during an outbreak of dengue fever and dengue haemorrhagic fever in Penang, Malaysia, were tested by a method involving antibody-dependent enhancement of infectivity in the mouse macrophage-like cell line, P388D1. 58 of 71 (81.7%) serologically positive cases yielded virus.

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