Primary Cutaneous B-cell Lymphomas

Abstract

B-cell lymphomas represent approximately 20% to 25% of primary cutaneous lymphomas. Within this group, most cases (>99%) are encompassed by 3 diagnostic entities: primary cutaneous marginal zone lymphoma, primary cutaneous follicle center lymphoma, and primary cutaneous diffuse large B-cell lymphoma, leg type. In this article, the authors present clinical, histopathologic, immunophenotypic, and molecular features of each of these entities and briefly discuss the rarer intravascular large B-cell lymphoma.

Keywords: Intravascular diffuse large B-cell lymphoma; Leg type; Primary cutaneous B-cell lymphoma; Primary cutaneous diffuse large B-cell lymphoma; Primary cutaneous follicle center lymphoma; Primary cutaneous marginal zone lymphoma.