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Comment
. 2017 Nov:66:414-415.
doi: 10.1016/j.bbi.2017.08.008. Epub 2017 Aug 10.

Charge density, not current density, is a more comprehensive safety measure of transcranial direct current stimulation

Pratik Y Chhatbar  1 , Mark S George  2 , Steven A Kautz  3 , Wuwei Feng  4
Affiliations
Comment

Charge density, not current density, is a more comprehensive safety measure of transcranial direct current stimulation

Pratik Y Chhatbar et al. Brain Behav Immun. 2017 Nov.
No abstract available

Keywords: Charge density; Current density; Dose; Stimulation duration; tDCS.

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Figures

Figure 1
Figure 1. Jackson et al. 2017 actually shows higher safety threshold than previously reported by Liebetanz et al. 2009
(A) Charge density plot. (B) Charge delivery per unit volume of the brain (arbitrary, assuming 2000× human to rat brain volume ratio - the total charge delivered to the human brain per unit volume is much smaller when compared with the rat brain.) Note the logarithmic scale on the azimuth in both the plots (from Chhatbar et al.).
See this image and copyright information in PMC

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References

    1. Jackson MP, et al. Safety parameter considerations of anodal transcranial Direct Current Stimulation in rats. Brain Behav Immun. 2017;64:152–161. doi: 10.1016/j.bbi.2017.04.008. - DOI - PMC - PubMed
    1. Liebetanz D, et al. Safety limits of cathodal transcranial direct current stimulation in rats. Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology. 2009;120:1161–1167. doi: 10.1016/j.clinph.2009.01.022. - DOI - PubMed
    1. Chhatbar PY, et al. Safety and tolerability of transcranial direct current stimulation to stroke patients - A phase I current escalation study. Brain Stimul. 2017;10:553–559. doi: 10.1016/j.brs.2017.02.007. - DOI - PMC - PubMed
    1. Chhatbar PY, George MS, Kautz SA, Feng W. Quantitative reassessment of safety limits of tDCS for two animal studies. Brain Stimulation. doi: https://doi.org/10.1016/j.brs.2017.07.008. - DOI - PMC - PubMed

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