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. 2017 Jul 26;3(4):e169.
doi: 10.1212/NXG.0000000000000169. eCollection 2017 Aug.

Updated nomenclature for human and mouse neurofibromatosis type 1 genes

Corina Anastasaki  1 , Lu Q Le  1 , Robert A Kesterson  1 , David H Gutmann  1
Affiliations

Updated nomenclature for human and mouse neurofibromatosis type 1 genes

Corina Anastasaki et al. Neurol Genet. .
No abstract available

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Figures

Figure 1
Figure 1. Proposed nomenclature for human NF1 and mouse Nf1 genes
(A) Schematic diagram illustrating the 57 exons of the human (top panel) and mouse (bottom panel) full-length transcripts, as well as the positions of the alternatively spliced exons (11alt12, 12alt13, 30alt31, and 56alt57). The proposed numbering system is denoted in each exon, while the prior numbering system is indicated below each exon. The RAS-GTPase-activating protein and the CRAL-TRIO domains are highlighted in gray. (B) Table detailing the nucleotides and amino acids spanning each of the 57 exons in human NF1 and mouse Nf1 genes. CRAl-TRIO domain = cellular retinaldehyde-binding protein and TRIO guanine exchange factor structural domain.
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