doi: 10.1016/0005-2728(87)90167-8.
Possible involvement of the 29 kDa protein in H+-ATPase in the action of cationic uncoupler of oxidative phosphorylation. Effect of the (o-phenanthroline)2-Cu2+ complex as a cationic uncoupler
- PMID: 2880605
- DOI: 10.1016/0005-2728(87)90167-8
Item in Clipboard
Possible involvement of the 29 kDa protein in H+-ATPase in the action of cationic uncoupler of oxidative phosphorylation. Effect of the (o-phenanthroline)2-Cu2+ complex as a cationic uncoupler
Biochim Biophys Acta.
.
Abstract
The divalent cation (o-phenanthroline)2-Cu2+ complex was found to uncouple oxidative phosphorylation in mitochondria. Its uncoupling activity depended on inorganic phosphate (Pi) in the incubation medium, and was inhibited by the SH-reagent N-ethylmaleimide, and retarded by ATP. The uncoupling by the (o-phenanthroline)2-Cu2+ complex was suggested to be due to its modification of sulfhydryl groups in the 29 kDa protein in H+-ATPase.
Similar articles
-
Unique action of a modified weakly acidic uncoupler without an acidic group, methylated SF 6847, as an inhibitor of oxidative phosphorylation with no uncoupling activity: possible identity of uncoupler binding protein.Biochim Biophys Acta. 1988 Mar 30;933(1):193-9. doi: 10.1016/0005-2728(88)90070-9. Biochim Biophys Acta. 1988. PMID: 2894856
-
A cyanine dye tri-S-C7(5). Phosphate-dependent cationic uncoupler of oxidative phosphorylation in mitochondria.Biochim Biophys Acta. 1983 Apr 22;723(1):7-15. doi: 10.1016/0005-2728(83)90003-8. Biochim Biophys Acta. 1983. PMID: 6830769
-
Uncoupler-reversible inhibition of mitochondrial ATPase by metal chelates of bathophenanthroline. I. General features.Biochim Biophys Acta. 1981 Dec 14;638(2):345-57. doi: 10.1016/0005-2728(81)90246-2. Biochim Biophys Acta. 1981. PMID: 6459123
-
Mitochondrial ATP-Pi exchange complex and the site of uncoupling of oxidative phosphorylation.Fed Proc. 1975 Jul;34(8):1699-706. Fed Proc. 1975. PMID: 1093889 Review.
-
Uncoupler-resistant mutants of bacteria.Microbiol Rev. 1990 Mar;54(1):52-65. doi: 10.1128/mr.54.1.52-65.1990. Microbiol Rev. 1990. PMID: 2181259 Free PMC article. Review.
Cited by
-
Uncouplers of oxidative phosphorylation.Environ Health Perspect. 1990 Jul;87:213-8. doi: 10.1289/ehp.9087213. Environ Health Perspect. 1990. PMID: 2176586 Free PMC article. Review.
-
The Joint Influence of Tl+ and Thiol-Modifying Agents on Rat Liver Mitochondrial Parameters In Vitro.Int J Mol Sci. 2022 Aug 11;23(16):8964. doi: 10.3390/ijms23168964. Int J Mol Sci. 2022. PMID: 36012228 Free PMC article.
-
Effects of copper-phenanthroline on pentachlorophenol-induced adaptation and cell death of Escherichia coli.Biomed Environ Sci. 2007 Apr;20(2):106-12. Biomed Environ Sci. 2007. PMID: 17624183 Free PMC article.
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Research Materials
Miscellaneous
