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Review
. 2017 Sep:117:1-11.
doi: 10.1016/j.critrevonc.2017.06.005. Epub 2017 Jun 13.

Bartholin gland cancer

Violante Di Donato  1 , Assunta Casorelli  2 , Erlisa Bardhi  2 , Flaminia Vena  2 , Claudia Marchetti  2 , Ludovico Muzii  2 , Pierluigi Benedetti Panici  2
Affiliations
Review

Bartholin gland cancer

Violante Di Donato et al. Crit Rev Oncol Hematol. 2017 Sep.

Erratum in

Abstract

Introduction: Bartholin gland carcinoma is an extremely rare condition. Because of its, phase III trials have not been carried out, there exists no unanimous consensus on treatment and guidelines are missing.

Methods: All studies reporting cases of Bartholin cancer were collected and screened for the evaluations. Baseline characteristics of studies were extracted and were queried in a database.

Results: A total number of 133 manuscripts collected were available for the review process, representing a total number of 275 reported cases. The histological type of Bartholin gland cancer was specified in 90.4% cases: 30.7% cases were squamous cell carcinoma, 29.6% adenoid cystic carcinoma, 25% adenocarcinomas. At multivariate analysis adenocarcinoma histotype and positive lymph node were statistical correlated with worse prognosis.

Conclusion: Bartholin gland cancer remains a challenge for gynecologic oncologists. To better understand and treat this disease, centralization to referral centers and design of multi institutional trials is crucial.

Keywords: Bartholin gland cancer; Bartholin gland carcinoma; Greater vestibular glands cancer; Major vestibular glands cancer.

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