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. 1987 Jan;39(1):47-9.
doi: 10.1111/j.2042-7158.1987.tb07161.x.

The effect of polycarbophil on the gastric emptying of pellets

R Khosla, S S Davis

The effect of polycarbophil on the gastric emptying of pellets

R Khosla et al. J Pharm Pharmacol. 1987 Jan.

Abstract

The influence of the putative bioadhesive, polycarbophil, on the gastric emptying of a pellet formulation, has been investigated in three fasted subjects. The pellets were radiolabelled with technetium-99m. Gastric emptying was measured using the technique of gamma scintigraphy. The pellets emptied from the stomach rapidly and in an exponential manner. Polycarbophil did not retard the gastric emptying of the pellets.

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