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Review
. 1987;325(6107):783-7.
doi: 10.1038/325783a0.

Bipolar affective disorders linked to DNA markers on chromosome 11

Review

Bipolar affective disorders linked to DNA markers on chromosome 11

J A Egeland et al. Nature. 1987.

Abstract

An analysis of the segregation of restriction fragment length polymorphisms in an Old Order Amish pedigree has made it possible to localize a dominant gene conferring a strong predisposition to manic depressive disease to the tip of the short arm of chromosome 11.

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