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. 2017 Oct;24(28):22673-22678.
doi: 10.1007/s11356-017-9887-3. Epub 2017 Aug 16.

Ozone generated by air purifier in low concentrations: friend or foe?

Larissa Vivan Cestonaro  1 , Ana Maria Marcolan  2 , Luciana Grazziotin Rossato-Grando  1 , Ana Paula Anzolin  1 , Gabriela Goethel  3 , Angélica Vilani  1 , Solange Cristina Garcia  3 , Charise Dallazem Bertol  4
Affiliations

Ozone generated by air purifier in low concentrations: friend or foe?

Larissa Vivan Cestonaro et al. Environ Sci Pollut Res Int. 2017 Oct.

Abstract

Ozone helps decontamination environments due to its oxidative power, however present toxicity when it is in high concentrations, by long periods of exposition. This study aimed to assess the safety of ozone generator air purifier at concentrations of 0.05 ppm in rats exposed to 3 and 24 h/day for 14 and 28 days. No significant differences are observed between groups in clinical signs, feed and water intake, relative body weight gain and relative weight of organs, macroscopy and microscopy of lungs, and oxidative plasma assay. In this exposure regime, ozone does not cause genotoxicity and no significant changes in pulmonary histology indicative of toxicity. Ozone generated in low concentrations, even in exposure regimes above the recommended is safe, both acute and sub-acute exposition.

Keywords: Acute toxicity; Comet assay; Micronucleus; Oxidative stress; Ozone; Rats; Sub-acute toxicity.

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