Tubocurarine and pancuronium inhibit evoked release of acetylcholine from the mouse hemidiaphragm preparation
- PMID: 2881567
- DOI: 10.1093/bja/59.2.226
Tubocurarine and pancuronium inhibit evoked release of acetylcholine from the mouse hemidiaphragm preparation
Abstract
Using a sensitive radioactive method that measures selectively the evoked release of acetylcholine, it was demonstrated that, when stimulating at 50 Hz, tubocurarine or pancuronium 2 X 10(-5) mol litre-1 or hexamethonium 10(-3) mol litre-1 significantly decreased the evoked release of acetylcholine in the mouse in vitro phrenic nerve-hemidiaphragm preparation.
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