Adding ketamine to an opioid in a patient-controlled analgesia device: is it really relevant in the pediatric population?

Souhayl Dahmani^{1

2

3}

Affiliations

¹ Department of Anesthesia and Intensive care, Robert Debre University Hospital, Paris, France.
² Paris Diderot University.
³ DHU PROTECT, INSERM U1141, Robert Debre University Hospital, Paris, France.

Comment

Souhayl Dahmani. Pain. 2017 Sep.

. 2017 Sep;158(9):1839.

doi: 10.1097/j.pain.0000000000000960.

Souhayl Dahmani^{1

2

3}

¹ Department of Anesthesia and Intensive care, Robert Debre University Hospital, Paris, France.
² Paris Diderot University.
³ DHU PROTECT, INSERM U1141, Robert Debre University Hospital, Paris, France.

No abstract available

Comment in

Reply.
Assouline B, Tramèr MR, Elia N. Assouline B, et al. Pain. 2017 Sep;158(9):1839-1840. doi: 10.1097/j.pain.0000000000000955. Pain. 2017. PMID: 28816886 No abstract available.

1. Assouline B, Tramèr MR, Kreienbühl L, Elia N. Benefit and harm of adding ketamine to an opioid in a patient-controlled analgesia device for the control of postoperative pain: systematic review and meta-analyses of randomized controlled trials with trial sequential analyses. PAIN 2016;157:2854–64.
1. Dahmani S, Michelet D, Abback PS, Wood C, Brasher C, Nivoche Y, Mantz J. Ketamine for perioperative pain management in children: a meta-analysis of published studies. Paediatr Anaesth 2011;21:636–52.
1. Michelet D, Hilly J, Skhiri A, Abdat R, Diallo T, Brasher C, Dahmani S. Opioid-sparing effect of ketamine in children: a meta-analysis and trial sequential analysis of published studies. Paediatr Drugs 2016;18:421–33.