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. 2017 Oct;107(10):1572-1576.
doi: 10.2105/AJPH.2017.303966. Epub 2017 Aug 17.

HIV Preexposure Prophylaxis and Condomless Sex: Disentangling Personal Values From Public Health Priorities

Affiliations

HIV Preexposure Prophylaxis and Condomless Sex: Disentangling Personal Values From Public Health Priorities

Sarah K Calabrese et al. Am J Public Health. 2017 Oct.

Abstract

Daily HIV preexposure prophylaxis (PrEP) is an effective form of HIV protection that remains unknown and inaccessible for many people in the United States despite receiving federal approval over five years ago. PrEP is supported by the public health community, but forgoing condoms while taking PrEP has proven controversial; this controversy may be contributing to the lag in PrEP uptake. We argue that limiting PrEP access based on anticipated or actual sexual behavior contradicts the goals of public health research and practice and is not scientifically justified. As evidence for the effectiveness of novel forms of biomedical HIV protection emerges, public health professionals need to accept new definitions of "protected sex" and ensure that their personal values do not override empirical evidence when determining public health priorities.

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Figures

FIGURE 1—
FIGURE 1—
Number of Cases of Sexually Transmitted Infections (STIs) Among Men Who Have Sex With Men (MSM): King County, WA, 2016 Note. The rising STI rates reported as an extension of previous trends when earlier data are included. A 2016 commentary by Alaei et al. presented STI incidence data from 2013–2016 to implicate preexposure prophylaxis (PrEP) uptake in the rising rates of STIs among MSM in King County, WA. STI rates increased between 2013 and 2016, but rates have been rising since 1997, with a pattern of accelerated growth beginning in 2008, 4 years before the approval of PrEP by the United States Food and Drug Administration. Source. Reproduced from the 2013 King County Sexually Transmitted Diseases Epidemiology Report, with subsequent extrapolated data points obtained from the 2015 and 2016 fourth quarter reports (http://www.kingcounty.gov/depts/health/communicable-diseases/hiv-std/patients/epidemiology.aspx).

Comment in

  • Calabrese et al. Respond.
    Calabrese SK, Underhill K, Mayer KH. Calabrese SK, et al. Am J Public Health. 2018 Jan;108(1):e1-e2. doi: 10.2105/AJPH.2017.304172. Am J Public Health. 2018. PMID: 29211531 Free PMC article. No abstract available.
  • PrEP-ared Against HIV, but Not Sexually Transmitted Infections.
    Algarin AB, Ibañez GE. Algarin AB, et al. Am J Public Health. 2018 Jan;108(1):e1. doi: 10.2105/AJPH.2017.304171. Am J Public Health. 2018. PMID: 29211533 Free PMC article. No abstract available.

References

    1. Fonner VA, Dalglish SL, Kennedy CE et al. Effectiveness and safety of oral HIV pre-exposure prophylaxis (PrEP) for all populations: a systematic review and meta-analysis. AIDS. 2016;30(12):1973–1983. - PMC - PubMed
    1. Alaei K, Paynter CA, Juan S-C, Alaei A. Using preexposure prophylaxis, losing condoms? Preexposure prophylaxis promotion may undermine safe sex. AIDS. 2016;30(18):2753–2756. - PubMed
    1. Doblecki-Lewis S, Jones D. Community federally qualified health centers as homes for HIV preexposure prophylaxis: perspectives from South Florida. J Int Assoc Provid AIDS Care. 2016;15(6):522–528. - PubMed
    1. Bush S, Magnuson D, Rawlings MK, Hawkins T, McCallister S, Mera Giler R. Racial characteristics of FTC/TDF for preexposure prophylaxis (PrEP) users in the US. Presented at: ASM Microbe; June 16–20, 2016; Boston, MA.
    1. Kojima N, Davey DJ, Klausner JD. Pre-exposure prophylaxis for HIV infection and new sexually transmitted infections among men who have sex with men. AIDS. 2016;30(14):2251–2252. - PubMed

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