Allele-Specific Gene Silencing: Another Step in the Inexorable Advance of Gene Therapy for Cardiac Arrhythmia Management
- PMID: 28819033
- DOI: 10.1161/CIRCRESAHA.117.311541
Allele-Specific Gene Silencing: Another Step in the Inexorable Advance of Gene Therapy for Cardiac Arrhythmia Management
Keywords: Editorials; RNA interference; arrhythmia mechanisms; arrhythmia treatment; congenital arrhythmia mutations; gene therapy.
Comment on
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Allele-Specific Silencing of Mutant mRNA Rescues Ultrastructural and Arrhythmic Phenotype in Mice Carriers of the R4496C Mutation in the Ryanodine Receptor Gene (RYR2).Circ Res. 2017 Aug 18;121(5):525-536. doi: 10.1161/CIRCRESAHA.117.310882. Epub 2017 Jun 15. Circ Res. 2017. PMID: 28620067
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