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Review
. 2017 Jun 2:27:82.
doi: 10.11604/pamj.2017.27.82.10902. eCollection 2017.

[Neuroendocrine carcinoma of the cervix: a case report and review of the literature]

[Article in French]
Soufiane Baggar  1 , Hajar Ouahbi  1 , Meryem Azegrar  1 , Fatima Zahra El M'rabet  1 , Samia Arifi  1 , Nawfel Mellas  1
Affiliations
Review

[Neuroendocrine carcinoma of the cervix: a case report and review of the literature]

[Article in French]
Soufiane Baggar et al. Pan Afr Med J. .

Abstract
in English, French

Small cell neuroendocrine carcinomas of the gynecologic tract are unusual, accounting for only 2% of the cervical cancers. Given the rarity of these tumors and the absence of randomized trials, their diagnosis and treatment programmes are difficult and are essentially based on those of neuroendocrine tumors of the lung. As in the case of the neuroendocrine tumors of the lung and despite multimodal treatment they are associated with a poor prognosis. We here report a new case of small cell neuroendocrine carcinoma of the cervix and, throught a literature review, we highlight the various aspects of this rare entity.

Les carcinomes neuroendocrines à petites cellules gynécologiques sont inhabituels, et ils ne représentent que 2% des tumeurs du col utérin. Compte tenu de leur rareté et de l’absence d’essais randomisés, la prise en charge diagnostique et thérapeutique de ces tumeurs est difficile et est essentiellement calquée sur celle des tumeurs neuroendocrines pulmonaires. A l’instar de ces dernières, et malgré un traitement multimodal, leur pronostic reste défavorable. Nous rapportons un nouveau cas de carcinome neuroendocrine du col à petites cellules et à travers les données de la littérature nous mettons le point sur les différents aspects de cette entité rare.

Keywords: Small cell neuroendocrine carcinoma; cervix; chemotherapy; radiation therapy.

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Figures

Figure 1
Figure 1
Prolifération tumorale peu différencié compatible avec un carcinome à petites cellules du col utérin
Figure 2
Figure 2
Coupe axiale de l’IRM pelvienne en séquence T2 montrant la masse tumorale de la berge externe du col utérin avec envahissement paramétrial gauche stade IIB selon la classification FIGO
See this image and copyright information in PMC

References

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