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. 2017 Sep;23(9):1581-1584.
doi: 10.3201/eid2309.170215.

Epidemiology of Neisseria gonorrhoeae Gyrase A Genotype, Los Angeles, California, USA

Ashima A Bhatti, Lao-Tzu Allan-Blitz, Mariana Castrejon, Romney M Humphries, Peera Hemarajata, Jeffrey D Klausner

Epidemiology of Neisseria gonorrhoeae Gyrase A Genotype, Los Angeles, California, USA

Ashima A Bhatti et al. Emerg Infect Dis. 2017 Sep.

Abstract

We investigated the epidemiology of the mutant gyrase A gene, a reliable predictor of ciprofloxacin resistance, in Neisseria gonorrhoeae infections at UCLA Health in Los Angeles, California, USA, during November 1, 2015-August 31, 2016. Among 110 patients with N. gonorrhoeae infections, 48 (44%) had the mutant gyrase A gene.

Keywords: California; Los Angeles; Neisseria gonorrhoeae; USA; antimicrobial resistance; bacteria; ciprofloxacin; epidemiology; genotype; gonorrhea; gyrA; gyrase A; gyrase A gene; men who have sex with men; sexually transmitted infections.

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Figures

Figure
Figure
Proportion of Neisseria gonorrhoeae infections genotyped for gyrase A gene by anatomic site, UCLA Health, Los Angeles, California, USA, November 1, 2015–August 31, 2016. A) Gyrase A gene; B) gyrase A mutant and wild-type genes.
See this image and copyright information in PMC

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