[INFECTIOUS CAUSES OF MISCARRIAGE]

Abstract

The aim of thiswork was to find out the infection causes and to assess the species composition of microflora of the vagina and cervix in women with miscarriage and chronic endometritis. The investigation of66 womenwith miscarriage (MC) with histological criteria of chronic endometritis (CE) has been done (main group). The control group consistsof 20 healthywomen of reproductiveage. The marked changes in the vagina and cervical canal mikroflora in women with MC and CE are registered. The latter is expressed is quantitative reduction of lactobacilli (20% and 75% in vagina, 7,5% and 60% in cervical canal in main and control groups correspondingly)andincrease in the number of opportunistic pathogens. Allthe aboveleads to imbalance of microflora of the vaginaand cervical canalthus contributing to theascentof infection from thelower part to the upper part of reproductive tract. These data regarding the disorders of vaginal and cervical microflora in women of the group indicates its pathogenic role in the development of miscarriage on the bases of chronic endometritis. The data obtainedallow to recommend theassessment of themicroflora of the vaginaandcervixin women withMC and CE forthe development of adequatepregravidar therapy.