Nano-technology contributions towards the development of high performance radioisotope generators: The future promise to meet the continuing clinical demand

Abstract

Nanostructured materials attracted considerable attention because of its high surface area to volume ratio resulting from their nano-scale dimensions. This class of sorbents is expected to have a potential impact on enhancement the efficacy of radioisotope generators for diagnostic and therapeutic applications in nuclear medicine. This review provides a summary on the importance of nanostructured materials as effective sorbents for the development of clinical-scale radioisotope generators and outlining the assessment of recent developments, key challenges and promising access to the near future.

Keywords: (188)W/(188)Re generators; (68)Ge/(68)Ga generator; (99)Mo/(99)Tc generators; Nano sorbents; Nanotechnology; Radioisotope generators; Radiopharmaceuticals.