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Observational Study
. 2017 Aug 21;7(8):e016925.
doi: 10.1136/bmjopen-2017-016925.

Effect of national implementation of utstein recommendation from the global resuscitation alliance on ten steps to improve outcomes from Out-of-Hospital cardiac arrest: a ten-year observational study in Korea

Young Taek Kim  1 , Sang Do Shin  2 , Sung Ok Hong  1 , Ki Ok Ahn  3 , Young Sun Ro  4 , Kyoung Jun Song  2 , Ki Jeong Hong  5
Affiliations
Observational Study

Effect of national implementation of utstein recommendation from the global resuscitation alliance on ten steps to improve outcomes from Out-of-Hospital cardiac arrest: a ten-year observational study in Korea

Young Taek Kim et al. BMJ Open. .

Abstract

Objectives: The Utstein ten-step implementation strategy (UTIS) proposed by the Global Resuscitation Alliance, a bundle of community cardiopulmonary resuscitation (CPR) programs to improve outcomes after out-of-hospital cardiac arrests (OHCAs), has been developed. However, it is not documented whether UTIS programs are associated with better outcomes or not. The study aimed to test the association between the UTIS programme and better outcomes after OHCA.

Methods: The study was a before- and after-intervention study. Adults OHCAs treated by emergency medical service (EMS) from 2006 to 2015 in Korea were collected, excluding patients witnessed by ambulance personnel and without outcomes. Phase 1 (2009-2011) after implementing three programs (national OHCA registry, obligatory CPR education, and public report of OHCA outcomes), and phase 2 (2012-2015) after implementing two programs (telephone-assisted CPR and EMS quality assurance programme) were compared with the control period (2006-2008) when no UTIS programme were implemented. The primary outcome was good neurological recovery (cerebral performance scale 1 or 2). We tested the association between the phases and outcomes, adjusting for confounders using a multivariate logistic regression model to calculate adjusted odds ratios (AORs) with 95% confidence intervals (CIs).

Results: A total of 1 28 888 eligible patients were analysed. The control, phase 1, and phase two study groups were 19.4%, 30.5%, and 50.0% of the whole, respectively. There were significant changes in pre-hospital ROSC (0.8% in 2006 and 7.1% in 2015), survival to discharge (3.0% in 2006 and 6.1% in 2015), and good neurological recovery (1.2% in 2006 and 4.1% in 2015). The AORs (95% CIs) for good neurological recovery were 1.82 (1.53-2.15) or phase 1 and 2.21 (1.78-2.75) for phase two compared with control phase.

Conclusion: The national implementation of the five UTIS programs was significantly associated with better OHCA outcomes in Korea.

Keywords: cardiopulmonary resuscitation; national health policy; out-of-hospital cardiac arrest; outcomes.

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Conflict of interest statement

Competing interests: No conflicts of interest are associated with this study.

Figures

Figure 1
Figure 1
National Implementation of Utstein Ten-step Implementation Strategy by study period. CPR, cardiopulmonary resuscitation; AED, automatic external defibrillation; KOHCAR, Korea out-of-hospital cardiac arrest registry; EMS, emergency medical services; T-CPR, telephone-assisted CPR; OA, quality assurance; OHCA, out-of-hospital cardiac arrest.
Figure 2
Figure 2
Study subjects. EMS, emergency medical service; OHCA, out-of-hospital cardiac arrest; CPR, cardiopulmonary resuscitation.
Figure 3
Figure 3
Longitudinal trend of outcomes in out-of-hospital cardiac arrest in Korea. ROSC, return of spontaneous circulation; CPC, cerebral performance scale.
See this image and copyright information in PMC

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