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. 2017 Aug 21;42(4):309-311.
doi: 10.1016/j.devcel.2017.08.006.

Protein Clustering Shapes Polarity Protein Gradients

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Protein Clustering Shapes Polarity Protein Gradients

Edwin Munro. Dev Cell. .
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Abstract

In this issue of Developmental Cell, Dickinson et al. (2017) and Rodriguez et al. (2017), along with Wang et al. (2017) in Nature Cell Biology, show how PAR protein oligomerization can dynamically couple protein diffusion and transport by cortical flow to control kinase activity gradients and polarity in the C. elegans zygote.

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