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Case Reports
. 1987 May;76(1):96-9.
doi: 10.1007/BF00283057.

X-linked immunodeficiency with hyperimmunoglobulinemia M appears to be linked to the DXS42 restriction fragment length polymorphism locus

E J Mensink, A Thompson, L A Sandkuyl, M E Kraakman, J D Schot, T Espanol, R K Schuurman
Case Reports

X-linked immunodeficiency with hyperimmunoglobulinemia M appears to be linked to the DXS42 restriction fragment length polymorphism locus

E J Mensink et al. Hum Genet. 1987 May.

Abstract

The gene involved in X-linked immunodeficiency with hyperimmunoglobulinemia M (XHM) was localized by the use of nine restriction fragment length polymorphic (RFLP) markers covering the entire X chromosome. Multipoint linkage analysis of RFLP data obtained in a three generation XHM pedigree indicates the Xq24-q27 area around the DXS42 RFLP locus as the most likely localization of the XHM locus.

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References

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