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Case Reports
. 1987 May;48(5):207-8.

Very low-dose neuroleptic treatment in two patients with agitation associated with Alzheimer's disease

S C Risse, T H Lampe, L Cubberley
  • PMID: 2883174
Case Reports

Very low-dose neuroleptic treatment in two patients with agitation associated with Alzheimer's disease

S C Risse et al. J Clin Psychiatry. 1987 May.

Abstract

Two agitated patients with Alzheimer's disease who either failed to respond or worsened with conventional low-dose neuroleptic and other pharmacologic treatment are described. Both patients demonstrated sustained improvement with very low-dose neuroleptics, one with haloperidol 0.125 mg and the other with thioridazine 5 mg. Clinical, pharmacokinetic, and pharmacodynamic factors that may have accounted for this response are discussed.

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