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Review
. 2017 Sep;8(3):173-180.
doi: 10.1177/2151458517713821. Epub 2017 Jul 7.

Hip Fractures in Elderly People: Surgery or No Surgery? A Systematic Review and Meta-Analysis

Cornelis L P van de Ree  1 , Mariska A C De Jongh  1   2 , Charles M M Peeters  3 , Leonie de Munter  1 , Jan A Roukema  1   4 , Taco Gosens  1   3
Affiliations
Review

Hip Fractures in Elderly People: Surgery or No Surgery? A Systematic Review and Meta-Analysis

Cornelis L P van de Ree et al. Geriatr Orthop Surg Rehabil. 2017 Sep.

Abstract

Introduction: Increasing numbers of patients with hip fractures also have advanced comorbidities. A majority are treated surgically. However, a significantly increasing percentage of medically unfit patients with unacceptably high risk of perioperative death are treated nonoperatively. Important questions about patients' prefracture quality of life (QOL) and future perspectives should be asked before considering different treatment options to assess what kind of treatment is advisable in frail elderly high-risk patients with a hip fracture.

Objective: The aim of this review was to provide an overview of differences in mortality, health-related QOL [(HR)QOL], functional outcome, and costs between nonoperative management (NOM) and operative management (OM) of hip fractures in patients above 65 years.

Methods: A systematic literature search was performed in EMBASE, OvidSP, PubMed, Cochrane Central, and Web of Science for observational studies and trials. Observational studies and randomized controlled trials comparing NOM with OM in hip fracture patients were selected. The methodological quality of the selected studies was assessed according to the Methodological Index for Nonrandomized Studies (MINORS) or Furlan checklist.

Results: Seven observational studies were included with a total of 1189 patients, of whom 242 (20.3%) were treated conservatively. The methodological quality of the studies was moderate (mean: 14.7, standard deviation [SD]: 1.5). The 30-day and 1-year mortalities were higher in the nonoperative group (odds ratio [OR]: 3.95, 95% confidence interval [CI]: 1.43-10.96; OR: 3.84, 95% CI: 1.57-9.41). None of the included studies compared QOL, functional outcome, or health-care costs between the 2 groups.

Conclusion: This systematic review and meta-analysis demonstrated that only a few studies with small number of patients comparing NOM with OM were published. A significantly higher 30-day and 1-year mortality was revealed in nonoperatively treated hip fracture patients. No data were found examining (HR)QOL and costs. Further work is needed to enable shared decision-making and to initiate NOM in frail elderly patients with advanced comorbidity and limited life expectancy.

Keywords: (non)operative treatment; elderly; hip fracture; mortality; quality of life.

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Conflict of interest statement

Declaration of Conflicting Interests: The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

Figures

Figure 1.
Figure 1.
Flow diagram; selection of articles: operative versus nonoperative management in elderly patients with a hip fracture.
Figure 2.
Figure 2.
Thirty-day mortality.
Figure 3.
Figure 3.
One-year mortality.
See this image and copyright information in PMC

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