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. 2017:1627:117-122.
doi: 10.1007/978-1-4939-7113-8_8.

Mouse Models of Corneal Scarring

Laure Rittié  1   2 , Audrey E K Hutcheon  3 , James D Zieske  4
Affiliations

Mouse Models of Corneal Scarring

Laure Rittié et al. Methods Mol Biol. 2017.

Abstract

Corneal scarring is an obligatory consequence of stroma corneal injury and is a major cause of decreased visual quality and vision loss worldwide. There are currently no satisfactory intervention therapies for corneal fibrosis. In this chapter, we describe well-established in vivo corneal wound models to allow researchers to investigate epithelial and stromal responses to corneal injury.

Keywords: Cornea; Epithelial debridement; Incision; Keratectomy; Mouse.

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