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. 2017 Aug 24;8(8):CD010211.
doi: 10.1002/14651858.CD010211.pub3.

Interconception care for women with a history of gestational diabetes for improving maternal and infant outcomes

Joanna Tieu  1 , Emily Shepherd, Philippa Middleton, Caroline A Crowther
Affiliations

Interconception care for women with a history of gestational diabetes for improving maternal and infant outcomes

Joanna Tieu et al. Cochrane Database Syst Rev. .

Abstract

Background: Gestational diabetes mellitus (GDM) is associated with adverse health outcomes for mothers and their infants both perinatally and long term. Women with a history of GDM are at risk of recurrence in subsequent pregnancies and may benefit from intervention in the interconception period to improve maternal and infant health outcomes.

Objectives: To assess the effects of interconception care for women with a history of GDM on maternal and infant health outcomes.

Search methods: We searched Cochrane Pregnancy and Childbirth's Trials Register (7 April 2017) and reference lists of retrieved studies.

Selection criteria: Randomised controlled trials, including quasi-randomised controlled trials and cluster-randomised trials evaluating any protocol of interconception care with standard care or other forms of interconception care for women with a history of GDM on maternal and infant health outcomes.

Data collection and analysis: Two review authors independently assessed study eligibility. In future updates of this review, at least two review authors will extract data and assess the risk of bias of included studies; the quality of the evidence will be assessed using the GRADE approach.

Main results: No eligible published trials were identified. We identified a completed randomised controlled trial that was designed to evaluate the effects of a diet and exercise intervention compared with standard care in women with a history of GDM, however to date, it has only published results on women who were pregnant at randomisation (and not women in the interconception period). We also identified an ongoing trial, in obese women with a history of GDM planning a subsequent pregnancy, which is assessing the effects of an intensive lifestyle intervention, supported with liraglutide treatment, compared with usual care. We also identified a trial that was designed to evaluate the effects of a weight loss and exercise intervention compared with lifestyle education also in obese women with a history of GDM planning a subsequent pregnancy, however it has not yet been published. These trials will be re-considered for inclusion in the next review update.

Authors' conclusions: The role of interconception care for women with a history of GDM remains unclear. Randomised controlled trials are required evaluating different forms and protocols of interconception care for these women on perinatal and long-term maternal and infant health outcomes, acceptability of such interventions and cost-effectiveness.

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Conflict of interest statement

Joanna Tieu: is supported by an NHMRC postgraduate scholarship and Arthritis Australia Ken Muirden fellowship (jointly funded by the Australian Rheumatology Association and Roche).

Emily Shepherd: none known.

Philippa Middleton: none known.

Caroline A Crowther: none known.

Figures

1
1
Study flow diagram.
See this image and copyright information in PMC

Update of

References

References to studies awaiting assessment

Koivusalo 2016 {published data only}
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References to ongoing studies

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NCT00924599 {published data only}
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References to other published versions of this review

Tieu 2012
    1. Tieu J, Middleton P, Crowther CA 10.1002/14651858.CD010211. Interconception care for women with a history of gestational diabetes for improving maternal and infant outcomes. Cochrane Database of Systematic Reviews 2012, Issue 11. [DOI: 10.1002/14651858.CD010211] - DOI - PubMed
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