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. 2017 Aug 17;22(33):30596.
doi: 10.2807/1560-7917.ES.2017.22.33.30596.

Ongoing large measles outbreak with nosocomial transmission in Milan, northern Italy, March-August 2017

Antonella Amendola  1   2 , Silvia Bianchi  1 , Elena R Frati  1 , Giulia Ciceri  1 , Marino Faccini  3 , Sabrina Senatore  3 , Daniela Colzani  1 , Anna Lamberti  3 , Melissa Baggieri  4 , Danilo Cereda  5 , Maria Gramegna  5 , Loredana Nicoletti  4 , Fabio Magurano  4 , Elisabetta Tanzi  1   2
Affiliations

Ongoing large measles outbreak with nosocomial transmission in Milan, northern Italy, March-August 2017

Antonella Amendola et al. Euro Surveill. .

Abstract

A large measles outbreak has been ongoing in Milan and surrounding areas. From 1 March to 30 June 2017, 203 measles cases were laboratory-confirmed (108 sporadic cases and 95 related to 47 clusters). Phylogenetic analysis revealed the co-circulation of two different genotypes, D8 and B3. Both genotypes caused nosocomial clusters in two hospitals. The rapid analysis of epidemiological and phylogenetic data allowed effective surveillance and tracking of transmission pathways.

Keywords: Epidemiology; Measles; Nosocomial transmission; Outbreaks; Phylogeny; Surveillance.

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Conflict of interest statement

Conflict of interest: None declared.

Figures

Figure 1
Figure 1
Geographical distribution of measles cases and clusters, with genotypes, Milan, 1 March–30 June 2017 (n = 187 cases)
Figure 2
Figure 2
Temporal distribution of measles cases and genotypes detected, Milan, 1 March–30 June 2017 (n = 187)
Figure 3
Figure 3
Neighbour-joining tree for nucleotide sequences of measles virus D8 and B3 variants causing nosocomial clusters in two hospitals, Milan, 1 March–30 June 2017 (n = 16)
See this image and copyright information in PMC

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