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Comment
. 2017 Aug 24;170(5):825-827.
doi: 10.1016/j.cell.2017.08.012.

Cancer Evolution Constrained by the Immune Microenvironment

Nicholas McGranahan  1 , Charles Swanton  2
Affiliations
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Cancer Evolution Constrained by the Immune Microenvironment

Nicholas McGranahan et al. Cell. .

Abstract

Tumor development is a Darwinian evolutionary process, involving the interplay between cancer subclones and the local immune microenvironment. These complex interactions are highlighted in this issue of Cell by the results from Jiménez-Sánchez et al. of a deep analysis of one patient with advanced serous carcinoma of the ovary.

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