doi: 10.1016/s0140-6736(87)92685-7.
Polymorphic DNA marker on X chromosome and manic depression
- PMID: 2884369
- DOI: 10.1016/s0140-6736(87)92685-7
Item in Clipboard
Polymorphic DNA marker on X chromosome and manic depression
Lancet.
.
Abstract
Heredity is an important factor in vulnerability to manic depression. A genetic linkage has been demonstrated between manic depression and coagulation factor IX at Xq27 with a TaqI polymorphism at the F9 locus in DNA samples from peripheral leucocytes of manic depressive probands and relatives in 10 informative families. Statistical analysis of the pedigrees gave a maximum lod score of 3.10 at a recombination fraction of 0.11, demonstrating a linkage between a manic depressive locus and the F9 locus in the Xq27 region.
Similar articles
-
Manic depressive illness not linked to factor IX region in an independent series of pedigrees.Genomics. 1990 Dec;8(4):648-55. doi: 10.1016/0888-7543(90)90251-o. Genomics. 1990. PMID: 1980485
-
Manic-depressive illness and linkage reanalysis in the Xq27-Xq28 region of chromosome X.Neuropsychobiology. 1995;31(2):58-63. doi: 10.1159/000119173. Neuropsychobiology. 1995. PMID: 7760986
-
X-chromosome markers and manic-depressive illness. Rejection of linkage to Xq28 in nine bipolar pedigrees.Arch Gen Psychiatry. 1990 Apr;47(4):366-73. doi: 10.1001/archpsyc.1990.01810160066010. Arch Gen Psychiatry. 1990. PMID: 2322087
-
[Genetics of manic depressive disorder].Med Arh. 1996;50(1-2):45-7. Med Arh. 1996. PMID: 9333681 Review. Croatian.
-
The question of X-linkage in bipolar manic-depressive illness.J Psychiatr Res. 1977;13(2):99-117. doi: 10.1016/0022-3956(77)90012-7. J Psychiatr Res. 1977. PMID: 320323 Review. No abstract available.
Cited by
-
Blue genes.BMJ. 1988 Oct 8;297(6653):871-2. doi: 10.1136/bmj.297.6653.871. BMJ. 1988. PMID: 3140960 Free PMC article. No abstract available.
-
A critical analysis of data presented in eight studies favouring X-linkage of bipolar illness with special emphasis on formal genetic aspects.Hum Genet. 1992 Nov;90(3):289-93. doi: 10.1007/BF00220081. Hum Genet. 1992. PMID: 1487243
-
The role of genetic factors in the etiology of the affective disorders.Behav Genet. 1990 Mar;20(2):235-50. doi: 10.1007/BF01067792. Behav Genet. 1990. PMID: 1972325
-
MOLECULAR GENETICS IN MENTAL ILLNESS.Med J Armed Forces India. 1994 Jul;50(3):211-214. doi: 10.1016/S0377-1237(17)31064-X. Epub 2017 Jun 27. Med J Armed Forces India. 1994. PMID: 28790557 Free PMC article. Review. No abstract available.
-
Genetic linkage analysis of manic depression in Iceland.J R Soc Med. 1993 Sep;86(9):506-10. J R Soc Med. 1993. PMID: 8105081 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical
Miscellaneous
