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Review
. 2017 Dec:37:35-40.
doi: 10.1016/j.coph.2017.08.006. Epub 2017 Aug 24.

Adipose tissue inflammation in obesity: a metabolic or immune response?

Emilie Stolarczyk  1
Affiliations
Free article
Review

Adipose tissue inflammation in obesity: a metabolic or immune response?

Emilie Stolarczyk. Curr Opin Pharmacol. 2017 Dec.
Free article

Abstract

Adipose tissue is not only a reservoir for energy, but also an immune organ. In the context of obesity, the development of insulin resistance is now recognised to be initiated by inflammation of the adipose tissue. However, the primary events triggering this inflammation are still unclear, as a complex combination of endocrine and immune factors act to regulate this adipose tissue microenvironment. Below we discuss the different factors involved and how they affect the biology of the adipose tissue in obesity.

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