Glanders and Melioidosis
- PMID: 28846298
- Bookshelf ID: NBK448110
Glanders and Melioidosis
Excerpt
Glanders is an infectious disease caused by Burkholderia mallei, a gram-negative aerobic nonmotile bacterium. Melioidosis is an infectious disease caused by Burkholderia pseudomallei, a gram-negative aerobic, motile bacterium. The two bacteria are closely related, and both can cause disease in animals and humans. Historically, glanders was a common disease of horses, donkeys, and mules. Melioidosis was first described as a case series of 38 patients in Rangoon, Burma, by pathologist Alfred Whitmore in 1912.
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References
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- Dance D. A glanders-like disease in Rangoon: Whitmore A. J Hyg 1913; 13: 1-34. Epidemiol Infect. 2005 Oct;133 Suppl 1:S9-S10. - PubMed
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- Chewapreecha C, Holden MT, Vehkala M, Välimäki N, Yang Z, Harris SR, Mather AE, Tuanyok A, De Smet B, Le Hello S, Bizet C, Mayo M, Wuthiekanun V, Limmathurotsakul D, Phetsouvanh R, Spratt BG, Corander J, Keim P, Dougan G, Dance DA, Currie BJ, Parkhill J, Peacock SJ. Global and regional dissemination and evolution of Burkholderia pseudomallei. Nat Microbiol. 2017 Jan 23;2:16263. - PMC - PubMed
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