Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Book

Cheyne Stokes Respirations

In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan.
.
Affiliations
Free Books & Documents
Book

Cheyne Stokes Respirations

Mohan Rudrappa et al.
Free Books & Documents

Excerpt

Cheyne-Stokes respiration is a type of breathing disorder characterized by cyclical episodes of apnea and hyperventilation. Although described in the early 19th century by John Cheyne and William Stokes, this disorder has received considerable attention in the last decade due to its association with heart failure and stroke, two major causes of mortality, and morbidity in developed countries. Unlike obstructive sleep apnea (OSA), which can be the cause of heart failure, Cheyne-Stokes respiration is believed to be a result of heart failure. The presence of Cheyne-Stokes respiration in patients with heart failure also predicts worse outcomes and increases the risk of sudden cardiac death. Despite increasing recognition and growing knowledge, Cheyne-Stokes respiration remains elusive, and patients have very limited treatment options.

PubMed Disclaimer

Conflict of interest statement

Disclosure: Mohan Rudrappa declares no relevant financial relationships with ineligible companies.

Disclosure: Pranav Modi declares no relevant financial relationships with ineligible companies.

Disclosure: Pradeep Bollu declares no relevant financial relationships with ineligible companies.

References

    1. Vargas-Ramirez L, Gonzalez-Garcia M, Franco-Reyes C, Bazurto-Zapata MA. Severe sleep apnea, Cheyne-Stokes respiration and desaturation in patients with decompensated heart failure at high altitude. Sleep Sci. 2018 May-Jun;11(3):146-151. - PMC - PubMed
    1. Granitza P, Kraemer JF, Schoebel C, Penzel T, Kurths J, Wessel N. Is dynamic desaturation better than a static index to quantify the mortality risk in heart failure patients with Cheyne-Stokes respiration? Chaos. 2018 Oct;28(10):106312. - PubMed
    1. Tinoco A, Mortara DW, Hu X, Sandoval CP, Pelter MM. ECG derived Cheyne-Stokes respiration and periodic breathing are associated with cardiorespiratory arrest in intensive care unit patients. Heart Lung. 2019 Mar-Apr;48(2):114-120. - PMC - PubMed
    1. Kim Y, Kim S, Ryu DR, Lee SY, Im KB. Factors Associated with Cheyne-Stokes Respiration in Acute Ischemic Stroke. J Clin Neurol. 2018 Oct;14(4):542-548. - PMC - PubMed
    1. Stellbrink C, Hansky B, Baumann P, Lawin D. [Transvenous neurostimulation in central sleep apnea associated with heart failure]. Herzschrittmacherther Elektrophysiol. 2018 Dec;29(4):377-382. - PubMed

Publication types

LinkOut - more resources